P036 Rechallenge Pemetrexed-Based Chemotherapy Provides an Option for Initially Benefitial Patients in Non-Small-Cell Lung Cancer

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Efficacy of Pemetrexed-based Chemotherapy in Comparison to Non-Pemetrexed-based Chemotherapy in Advanced, ALK+ Non-Small Cell Lung Cancer

PURPOSE Previous retrospective studies suggest that anaplastic lymphoma kinase (ALK) mutation-positive (ALK+) non-small cell lung cancer (NSCLC) patients are sensitive to pemetrexed. To determine its efficacy, we retrospectively evaluated clinical outcomes of pemetrexed-based chemotherapy in patients with ALK+ NSCLC. MATERIALS AND METHODS We identified 126 patients with advanced, ALK+ NSCLC w...

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Epiphora following chemotherapy with pemetrexed in patients with advanced non-small cell lung cancer

Copyright © 2017 The Korean Association of Internal Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. pISSN 1226-3303 eISSN 2005-664...

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Chemotherapy for non-small cell lung cancer in elderly patients.

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Pemetrexed for the treatment of non-small cell lung cancer.

INTRODUCTION Non-small cell lung cancer (NSCLC) is a major cause of cancer-related death worldwide. Although advanced NSCLC is still incurable, various anti-neoplastic agents have become available for the treatment of this disease. Pemetrexed , a multi-target folate antagonist, has improved the survival of non-squamous NSCLC patients. Currently, pemetrexed is approved for first-line treatment i...

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ژورنال

عنوان ژورنال: Journal of Thoracic Oncology

سال: 2018

ISSN: 1556-0864

DOI: 10.1016/j.jtho.2018.10.059